This technology provides a suction regulating system of a vacuum cleaner and a vacuum cleaner with the suction regulating system. The suction regulating system of a vacuum cleaner includes a suction device for generating suction, a suction pipe connected with the suction device, a control unit, a communication connection between the control unit and the suction device, and a suction regulating system of a vacuum cleaner. The detection device includes a piezoelectric piece fixed in the vacuum pipe, an amplification comparison module connected with the piezoelectric piece, and a communication connection between the amplification comparison module and the control unit. When the dust-containing air enters the vacuum pipe, the dust will impact on the vacuum pipe. The piezoelectric sheet in the channel causes the piezoelectric sheet to deform. The control unit can automatically control the suction force of the suction device according to the deformation of the piezoelectric sheet. The cost is low, and the energy consumption of the vacuum cleaner can be effectively reduced while ensuring the cleaning effect.